The development of a new class of inhibitors for betaine-homocysteine S-methyltransferase

J Pícha, V Vaněk, M Buděšínský, J Mládková…

Index: European Journal of Medicinal Chemistry, , vol. 65, p. 256 - 275

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Citation Number: 7

Abstract

... European Journal of Medicinal Chemistry. ... H 2 SO 4 , reflux, 12 h (84%); (g) acetic anhydride, reflux, 6 h (79%); (h) sodium borohydride, THF, rt, 3 d (72%); (i) HBr, ethanol, rt, 3 d (89%); (j) (i) Na, NH 3 (l), (ii) ethyl 5-bromovalerate, −33 °C, (iii) NaOH, water, 56% (36); (k) (i) Na ...