Quadracyclic Adenine: A Non??Perturbing Fluorescent Adenine Analogue

A Dierckx, FA Miannay, N Ben Gaied…

Index: Dierckx, Anke; Miannay, Francois-Alexandre; Ben Gaied, Nouha; Preus, Soren; Bjoerck, Markus; Brown, Tom; Wilhelmsson, L. Marcus Chemistry - A European Journal, 2012 , vol. 18, # 19 p. 5987 - 5997

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Citation Number: 18

Abstract

Abstract Fluorescent-base analogues (FBAs) comprise a group of increasingly important molecules for the investigation of nucleic acid structure and dynamics as well as of interactions between nucleic acids and other molecules. Here, we report on the synthesis, detailed spectroscopic characterisation and base-pairing properties of a new environment- sensitive fluorescent adenine analogue, quadracyclic adenine (qA). After developing an ...

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