Iron??Catalyzed ortho??Selective Functionalization of Phenols: A Straightforward Strategy towards the 2′??Hydroxyphenyl??1, 2??dione Skeleton

X Guo, W Li, Z Li

Index: Guo, Xingwei; Li, Wenjuan; Li, Zhiping European Journal of Organic Chemistry, 2010 , # 30 p. 5787 - 5790

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Citation Number: 17

Abstract

Direct functionalization of phenolic C–H bond has attracted much attention because phenols are one of the most important aromatic compounds in nature and industry.1 The Friedel–Crafts reaction is one of the most well-known and powerful strategies for such a transformation.2 However, usually it is difficult to control the regio- and/or monoselectivity if no directing group is present in the benzene ring (Scheme 1, pathway A). Although ...