Efficient synthesis of quinoxalines with hypervalent iodine as a catalyst
CY Chen, WP Hu, MC Liu, PC Yan, JJ Wang, MI Chung
Index: Chen, Chung-Yu; Hu, Wan-Ping; Liu, Mei-Chun; Yan, Pi-Cheng; Wang, Jeh-Jeng; Chung, Mei-Ing Tetrahedron, 2013 , vol. 69, # 46 p. 9735 - 9741
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Citation Number: 12
Abstract
Abstract Various biologically important quinoxalines were efficiently synthesized in excellent yields via one-pot reaction between 1, 2-diaminobenzenes and internal alkynes. The method utilizes inexpensive and readily available hypervalent iodine source, such as (diacetoxyiodo) benzene (PhI (OAc) 2) and proved to be a better alternative as compared to expensive transition metal catalysts. Quinoxaline 4i [(2-phenyl-3-(3, 4, 5-trimethoxy phenyl ...
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