Direct 2-arylation of thiophene using low loading of a phosphine-free palladium catalyst
S Bensaid, J Roger, K Beydoun, D Roy…
Index: Bensaid, Souhila; Roger, Julien; Beydoun, Kassem; Roy, David; Doucet, Henri Synthetic Communications, 2011 , vol. 41, # 23 p. 3524 - 3531
Full Text: HTML
Citation Number: 8
Abstract
Abstract The direct coupling of aryl halides with thiophene would be a considerable advantage for sustainable development because of only HBr associated with a base as by- product is formed and the number of steps to prepare these compounds is less than in more classical coupling reactions. We observed that through the use of only 0.2 mol% Pd (OAc) 2 as the catalyst, a range of aryl bromides undergoes coupling via a CH bond activation/ ...
Related Articles:
[Snelders, Dennis J. M.; Kreiter, Robert; Firet, Judith J.; Van Koten, Gerard; Gebbink, Robertus J. M. Klein Advanced Synthesis and Catalysis, 2008 , vol. 350, # 2 p. 262 - 266]
[Dalton Transactions, , vol. 40, # 35 p. 8996 - 9003]
[Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 23 p. 7151 - 7154]
[Wu, Wei-Yi; Lin, Tze-Chiao; Takahashi, Tamotsu; Tsai, Fu-Yu; Mou, Chung-Yuan ChemCatChem, 2013 , vol. 5, # 4 p. 1011 - 1019]
Aryl-aryl cross coupling on a solid support using zinc organic reagents and palladium catalysis
[Tetrahedron Letters, , vol. 37, # 31 p. 5491 - 5494]