Stereoselective Synthesis of (E)??Hydroxystilbenoids by Ruthenium??Catalyzed Cross??Metathesis

K Ferré??Filmon, L Delaude…

Index: Ferre-Filmon, Karine; Delaude, Lionel; Demonceau, Albert; Noels, Alfred F. European Journal of Organic Chemistry, 2005 , # 15 p. 3319 - 3325

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Citation Number: 21

Abstract

Abstract An efficient and highly stereoselective synthetic procedure is reported for the construction of symmetrical and unsymmetrical (E)-polymethoxystilbene and (E)- polyhydroxystilbene derivatives. The strategy rests on a cross-metathesis reaction catalyzed by stable, well-defined (alkylidene) ruthenium complexes, in particular the second- generation Grubbs catalyst [RuCl 2 (= CHPh)(SIMes)(PCy 3)][SIMes= 1, 3-bis (2, 4, 6- ...

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