Development of the Route of Manufacture of an Oral H1− H3 Antagonist
G Bret, SJ Harling, K Herbal, N Langlade…
Index: Organic Process Research and Development, , vol. 15, # 1 p. 112 - 122
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Citation Number: 9
Abstract
... Organic Process Research & Development. ... Second, the process was quite lengthy, with several solvent and salt swaps. ... procedures to try and improve the selectivity for the desired product, and also try to streamline the hydrogenation and isolation procedure, ideally removing ...
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