In vitro antimicrobial and antimycobacterial activity of some chalcones and their derivatives
D Patel, P Kumari, NB Patel
Index: Patel, Divyesh; Kumari, Premlata; Patel, Navin B. Medicinal Chemistry Research, 2013 , vol. 22, # 2 p. 726 - 744
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Citation Number: 8
Abstract
Abstract In this study, novel series of chalcone derivatives, namely, 4-[4-(3-phenyl-acryloyl)- phenylamino]-chromen-2-one (5a–k) have been synthesized from the intermediate 4-(4- acetyl-phenylamino)-chromen-2-one (4). Cyclization reaction of chalcone (5a–k) with hydrazine hydrate, guanidine nitrate, and malononitrile gives the corresponding 4-[4-(1- acetyl-5-phenyl-4, 5-dihydro-1 H-pyrazol-3-yl)-phenylamino]-chromen-2-one (6a–k), 4-[4-( ...
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