Chemistry–A European Journal

Iron??Catalyzed N??Arylations of Amides

A Correa, S Elmore, C Bolm

Index: Correa, Arkaitz; Elmore, Simon; Bolm, Carsten Chemistry - A European Journal, 2008 , vol. 14, # 12 p. 3527 - 3529

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Citation Number: 4

Abstract

Transition metal-catalyzed N-arylation of amides constitutes a powerful CÀN bond-forming process that has been extensively utilized in pharmaceutical and medicinal chemistry.[1] Despite remarkable advances in both palladium-[2] and copper-catalyzed [3] reactions of this type, the development of alternative catalysts involving more cost-efficient, nontoxic, and environmentally friendly metals to effect the target process remains an issue of scientific ...