The development of cyclic sulfolanes as novel and high-affinity P2 ligands for HIV-1 protease inhibitors

AK Ghosh, HY Lee, WJ Thompson…

Index: Journal of Medicinal Chemistry, , vol. 37, # 8 p. 1177 - 1188

Full Text: HTML

Citation Number: 58

Abstract

... The desired cis isomer 15 was separated from the mixture by silica gel chromatography with 25 % ethyl acetate in hexane. 0022-2623/94/1837-117'7$04.50/0 0 1994 American Chemical Society Page 2. 1178 Journal of Medicinal Chemistry, 1994, Vol. 37, No. 8 ...

Related Articles:

Studies toward the large-scale synthesis of the HIV proteinase inhibitor Ro 31-8959

[Parkes, Kevin E. B.; Bushnell, David J.; Crackett, Peter H.; Dunsdon, Stephen J.; Freeman, Andrew C.; et al. Journal of Organic Chemistry, 1994 , vol. 59, # 13 p. 3656 - 3664]

Reduction of peptide character of HIV protease inhibitors that exhibit nanomolar potency against multidrug resistant HIV-1 strains

[Journal of Medicinal Chemistry, , vol. 46, # 9 p. 1764 - 1768]

Studies toward the large-scale synthesis of the HIV proteinase inhibitor Ro 31-8959

[Parkes, Kevin E. B.; Bushnell, David J.; Crackett, Peter H.; Dunsdon, Stephen J.; Freeman, Andrew C.; et al. Journal of Organic Chemistry, 1994 , vol. 59, # 13 p. 3656 - 3664]

Studies toward the large-scale synthesis of the HIV proteinase inhibitor Ro 31-8959

[Journal of Organic Chemistry, , vol. 59, # 13 p. 3656 - 3664]

Studies toward the large-scale synthesis of the HIV proteinase inhibitor Ro 31-8959

[Parkes, Kevin E. B.; Bushnell, David J.; Crackett, Peter H.; Dunsdon, Stephen J.; Freeman, Andrew C.; et al. Journal of Organic Chemistry, 1994 , vol. 59, # 13 p. 3656 - 3664]

More Articles...