Preparation of Some Substituted 2-Methyl-3-indoleacetic Acids1, 2

FJ Stevens, DH Higginbotham

Index: Stevens; Higginbotham Journal of the American Chemical Society, 1954 , vol. 76, p. 2206

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Citation Number: 8

Abstract

b-hlethyl-5-bronio-, 2-methyl-7-bromo-, 2-inethyl-5, 7-dibromo-, 2, 7-dimethyl-5-bromo-, 2- mcthyl-4-chloro-7-inatho. cydiid 2-methyl-(4 or 6)-chloro-3-indoleacetic acids have been prepared from the properly substituted phenylhydrazones of ethyl levulinate by the Fischer indole synthesis 2-iMethoxy-5-chlorophenylhydrazine, the hydrochloride and acetyl derivatives have been prepared.