Pd-catalysed asymmetric Suzuki–Miyaura reactions using chiral mono-and bidentate phosphorus ligands

…, E Zangrando, S Gladiali, C Godard, C Claver

Index: Castillo, Angelica Balanta; Perandones, Bernabe F.; Zangrando, Ennio; Gladiali, Serafino; Godard, Cyril; Claver, Carmen Journal of Organometallic Chemistry, 2013 , vol. 743, p. 31 - 36

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Citation Number: 6

Abstract

Abstract A series of monodentate and bidentate chiral phosphorus based ligands including diphosphites and diphosphonites derived from carbohydrates were tested in the asymmetric Suzuki coupling of aryl halides with 2-substituted 1-naphthylboronic acids. Good activities and selectivities were achieved, although modest ee's were obtained (up to 37%). The X-ray structure of PtCl 2 (12) bearing the C 2-symmetry diphosphite ligand 12 derived from ...