Tetrahedron

Reactiohs with α-thiocarbamoylcinnamonitriles: Synthesis of pyrazolo [1, 5-a] pyrimidines

SM Hussain, AM El-Reedy, SA El-Sharabasy

Index: Hussain, Sohair Mohamed; El-Reedy, Ahmed Mohamed; El-Sharabasy, Salwa Ahmed Tetrahedron, 1988 , vol. 44, # 1 p. 241 - 246

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Citation Number: 24

Abstract

Whereas each of α-thiocarbamoyl-and α-cyanomalononitrile derivatives 1a and 1d reacted with benzamidine (2) hydrochloride to give only 4-amino-6-(4-chlorophenyl)-2-phenyl-5- pyrimidine-carbonitrile (5a), they react with 5-amino-3-phenylpyrazole (6) to yield the two ...