Tetrahedron letters

Highly enantioselective resolution of terminal epoxides with cross-linked polymeric salen–Co (III) complexes

Y Song, H Chen, X Hu, C Bai, Z Zheng

Index: Song, Yuming; Chen, Huilin; Hu, Xinquan; Bai, Changmin; Zheng, Zhuo Tetrahedron Letters, 2003 , vol. 44, # 37 p. 7081 - 7085

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Citation Number: 36

Abstract

Crosslinked polymeric salen–Co (III) complexes derived from a novel dialdehyde and a trialdehyde were synthesized and employed in the hydrolytic kinetic resolution (HKR) of terminal epoxides. Up to 99% ee were obtained with only 0.16–0.02 mol% of catalyst (based on catalytic unit).