Tetrahedron Letters

Y (NO 3) 3· 6H 2 O catalyzed regioselective ring opening of epoxides with aliphatic, aromatic, and heteroaromatic amines

MJ Bhanushali, NS Nandurkar, MD Bhor…

Index: Bhanushali, Mayur J.; Nandurkar, Nitin S.; Bhor, Malhari D.; Bhanage, Bhalchandra M. Tetrahedron Letters, 2008 , vol. 49, # 22 p. 3672 - 3676

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Citation Number: 52

Abstract

Yttrium nitrate hexahydrate [Y (NO3) 3· 6H2O] was found to be an efficient catalyst for selective ring opening of epoxides with aliphatic, aromatic, and heteroaromatic amines at room temperature under solvent-free conditions. The system tolerated a variety of hindered and functionalized epoxides/amines and afforded the desired β-amino alcohols at low catalyst concentration.