Pd-m BDPP-Catalyzed Regioselective Internal Arylation of Electron-Rich Olefins by Aryl Halides

…, N Berry, N Thomson, A Pettman, Z Hyder…

Index: Liu, Shifang; Berry, Neil; Thomson, Nick; Pettman, Alan; Hyder, Zeynab; Mo, Jun; Xiao, Jianliang Journal of Organic Chemistry, 2006 , vol. 71, # 19 p. 7467 - 7470

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Citation Number: 33

Abstract

meso-2, 4-Bis (diphenylphosphino) pentane (m BDPP) has proved to be an effective regiocontrolling ligand for palladium-catalyzed internal arylation by aryl bromides of electron- rich olefins in a common solvent DMSO with no need for any halide scavengers. The arylation of the benchmark electron-rich olefin butyl vinyl ether took place smoothly to afford exclusively α-arylated product with high isolated yields. The better performance of m ...

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