Novel and Gram??Scale Green Synthesis of Flutamide

BP Bandgar, SS Sawant

Index: Bandgar; Sawant Synthetic Communications, 2006 , vol. 36, # 7 p. 859 - 864

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Citation Number: 13

Abstract

Abstract Isobutyric acid in the presence of cyanuric chloride and N??methylmorpholine was converted into active ester 3 at 0–5° C, and it was subsequently treated with 3?? aminobenzotrifluoride 4 at 25° C to furnish corresponding amide 5. This amide finally, on