A New Synthetic Approach to Substituted 1 (2 H)-Phenanthrenones Based on the Ceric Ammonium Nitrate-Promoted Oxidative Addition of 3-Aryl-1-[(trimethylsilyl) oxy] …
P Lupattelli, R Ruzziconi, P Scafato…
Index: Lupattelli, Paolo; Ruzziconi, Renzo; Scafato, Patrizia; Alunni, Sergio; Paolobelli, Anna Belli Journal of Organic Chemistry, 1998 , vol. 63, # 13 p. 4506 - 4509
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Citation Number: 11
Abstract
A phenanthrene nucleus is the basis of an important class of biologically and pharmaceutically active compounds, 1 including hormone stimulants, 1a enzyme inhibitors, 1b, d steroids and their aza analogues, 1c, o analgesic and antinflammatory drugs, 1g and antibiotics. 1o In most cases, they are accessible through dihydrophenanthrenones, whose synthesis has attracted the interest of several researchers since the beginning of this ...
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