Tandem indole C–H alkenylation/arylation for tetra-substituted alkene synthesis

LL Suarez, MF Greaney

Index: Suarez, Laura Lopez; Greaney, Michael F. Chemical Communications, 2011 , vol. 47, # 28 p. 7992 - 7994

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Citation Number: 31

Abstract

Alkynyl indoles undergo a novel sequence of Pd-catalysed indole C–H activation/alkyne carbopalladation/arylation, with diaryliodonium salts providing the aryl components. An array of functionalised indole alkenes have been prepared in good to excellent yield, with the reaction being selective for the Z-alkene.