Amine Exchange in Formamidines: An Experimental and Theoretical Study

…, L Xing, R Wang, A Petitjean

Index: Capela, Marinha Df.; Mosey, Nicholas J.; Xing, Liyan; Wang, Ruiyao; Petitjean, Anne Chemistry - A European Journal, 2011 , vol. 17, # 16 p. 4598 - 4612

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Citation Number: 6

Abstract

Abstract N [BOND] H-containing formamidines combine a reasonably strong association to carboxylic acids to form complexes of well-defined geometries with a simultaneous proton- induced electrophilicity enhancement that allows for the exchange of their amine portion. The N [DOUBLE BOND] C (H)[BOND] NH fragment, therefore, undergoes “imine-like” exchange with N-containing nucleophiles. Because of the prototropic equilibrium, the N [ ...