Chemistry Letters
Practical Preparation of Chiral 4-Substituted 2-Oxazolidinones.
T Ishizuka, K Kimura, S Ishibuchi, T Kunieda
Index: Ishizuka, Tadao; Kimura, Koreichi; Ishibuchi, Seigo; Kunieda, Takehisa Chemistry Letters, 1992 , # 6 p. 991 - 994
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Citation Number: 13
Abstract
A versatile and practical route to both enantiomers of a wide variety of 4-substituted 2- oxazolidinones from the parent heterocycle is provided by regioselective substitutions via 4- methoxy derivative followed by chromatographic separation of the diastereomers derived from N-2-exo-methoxy-1-apocamphanecarbonylation.