Synthesis of 1, 2-dihydropyrrolo [1, 2-c] pyrimidin-1-ones

M Alvarez, D Fernández, JA Joule

Index: Alvarez, Mercedes; Fernandez, David; Joule, John A. Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 3 p. 249 - 255

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Citation Number: 31

Abstract

1, 2-Dihydropyrrolo [1, 2-c] pyrimidin-1-ones 2 have been synthesised from pyrrole. We have developed a versatile procedure for the introduction of substituents into the pyrrolopyrimidinones 2, at positions 5 or 7 as desired, and as required by our plans for the synthesis of the variolin type sea alkaloids.