Preparation and reactions of 3, 4??dihydro??2H??pyran??2??ones

…, MM Mishrikey, SL Abdoul??Ela

Index: El-Kholy, Ibrahim El-Sayed; Mishrikey, Morcos Michael; Abdoul-Ela, Salah Loutfi Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1329 - 1334

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Citation Number: 6

Abstract

Abstract The Michael reaction of ethyl cinnamates with deoxybenzoin gave ethyl 3, 4, 5- triaryl-5-oxopentanoates which were hydrolysed to the corresponding acids. The latter could be cyclized to the respective 3, 4-dihydro-2H-pyran-2-ones which underwent ring opening with several nucleophiles to the corresponding acid derivatives. However, their reaction with ammonium acetate led to the formation of 3, 4-dihydro-2-pyridones. The 3, 4-dihydro-2- ...