The Journal of organic chemistry

Molecular imprinting of carboxylic acids employing novel functional macroporous polymers

D Spivak, KJ Shea

Index: Spivak, David; Shea, Kenneth J. Journal of Organic Chemistry, 1999 , vol. 64, # 13 p. 4627 - 4634

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Citation Number: 103

Abstract

Imprinted network polymers incorporating basic functional groups were developed to assess the binding and specificity of carboxylic acids. The binding affinities were determined using t- BOC-phenylalanine and 2-phenylbutyric acid as templates and substrates. Chiral selectivity for the enantiomers of t-BOC-phenylalanine was found for polymers incorporating adenine or 2-aminopyridine functionality. Chiral selectivity in the case of (R)-(-)-2-phenylbutyric ...