Direct thiophene arylation catalysed by palladium
C Gozzi, L Lavenot, K Ilg, V Penalva, M Lemaire
Index: Gozzi, Christel; Lavenot, Laurence; Ilg, Kerstin; Penalva, Vincent; Lemaire, Marc Tetrahedron Letters, 1997 , vol. 38, # 51 p. 8867 - 8870
Full Text: HTML
Citation Number: 93
Abstract
Direct thiophene arylation using a Heck-type reaction with Pd (OAc) 2NBu 4Br as catalytic system is reported. Reactions with 2-and 3-substituted thiophenes have shown that substituent nature and position influence the cross-coupling. In particular, the substitution is regiospecific when the heterocycle is 2-substituted with an electron withdrawing group.
Related Articles:
Extension of the Heck reaction to the arylation of activated thiophenes
[Lavenot; Gozzi; Ilg; Orlova; Penalva; Lemaire Journal of Organometallic Chemistry, 1998 , vol. 567, # 1-2 p. 49 - 55]
[Dai, Heng; Yang, Xueyan; Tan, Xiaoping; Su, Fawu; Cheng, Xiaohong; Liu, Feng; Tschierske, Carsten Chemical Communications, 2013 , vol. 49, # 90 p. 10617 - 10619]
[Dai, Heng; Yang, Xueyan; Tan, Xiaoping; Su, Fawu; Cheng, Xiaohong; Liu, Feng; Tschierske, Carsten Chemical Communications, 2013 , vol. 49, # 90 p. 10617 - 10619]
Nematic 2, 5-disubstituted thiophenes
[Campbell, Neil L.; Duffy, Warren L.; Thomas, Gareth I.; Wild, Janine H.; Kelly, Stephen M.; Bartle, Kevin; O'Neill, Mary; Minter, Vicky; Tuffin, Rachel P. Journal of Materials Chemistry, 2002 , vol. 12, # 9 p. 2706 - 2721]