Journal of the American Chemical Society

Nitrogen Mustards

E Wilson, M Tishler

Index: Wilson; Tishler Journal of the American Chemical Society, 1951 , vol. 73, p. 3635,3636

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Citation Number: 27

Abstract

The discovery of nitrogen mustards (I) as chemotherapeutic agents in the treatment of certain neoplastic diseases '-'prompted a cooperative reasearch program with the Sloan- Kettering Institute for Cancer Research in order to explore further the potentialities of nitrogen mustards. We have prepared a large number of nitrogen mustards and related compounds, which have were prepared by the action of a thionyl halide on the ...