A New Method of Introducing SCH3 and SCD3 Groups to Phosphorothioates

T Liu, X Cui, Z Yu, C Li

Index: Liu, Tianzhen; Cui, Xiaoxue; Yu, Zhifang; Li, Chunbao Phosphorus, Sulfur and Silicon and the Related Elements, 2012 , vol. 187, # 5 p. 606 - 611

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Abstract

A new synthesis of phosphorothioates starting from phosphites and cyanuric chloride (TCT)-activated DMSO is reported herein. This method enables the incorporation of SCH 3 and SCD 3 groups into phosphorothioates in good yields. The labeling purities of the products are excellent. ... A new synthesis of phosphorothioates starting from phosphites and cyanuric chloride (TCT)-activated DMSO is reported herein. This method enables the incorporation of SCH 3 and SCD 3 ...

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