Synthesis of hydroxylated and methoxylated polybrominated diphenyl ethers− natural products and potential polybrominated diphenyl ether metabolites

G Marsh, R Stenutz, A Bergman

Index: Marsh, Goeran; Stenutz, Roland; Bergman, Ake European Journal of Organic Chemistry, 2003 , # 14 p. 2566 - 2576

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Citation Number: 148

Abstract

Abstract Hydroxylated and methoxylated polybrominated diphenyl ethers (OH-PBDEs and MeO-PBDEs) may be natural products or they may be formed as metabolites of polybrominated diphenyl ethers (PBDEs), frequently used as flame retardants. The aim of this work was to synthesize authentic OH-and MeO-PBDE reference standards for analytical and toxicological studies. Brominated phenoxybenzaldehydes were prepared either by ...