Tetrahedron Letters

Assembly of indolo [1, 2-c] quinazolines using ZnBr 2-promoted domino hydroamination–cyclization

M Xu, K Xu, S Wang, ZJ Yao

Index: Xu, Min; Xu, Ke; Wang, Shaozhong; Yao, Zhu-Jun Tetrahedron Letters, 2013 , vol. 54, # 35 p. 4675 - 4678

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Citation Number: 10

Abstract

Abstract An efficient protocol to generate indolo [1, 2-c] quinazolines from acyclic alkyne substrates by ZnBr 2-promoted domino hydroamination–cyclization has been established. The dichotomous properties of zinc salts involving alkynophilicity and oxophilicity assure a