Synthesen in der Isochinolinreihe: Zur Ätherspaltung 6, 7, 8-trimethoxy-substituierter Isochinolinverbindungen mit wässeriger Salzsäure

A Brossi, M Baumann, R Borer

Index: Brossi,A. et al. Monatshefte fuer Chemie, 1965 , vol. 96, p. 25 - 36

Full Text: HTML

Citation Number: 8

Abstract

Abstract Treatment of the 6, 7, 8-trimethoxy-substituted 1, 2, 3, 4-tetrahydroisoquinoline I with 20% aqueous HCl yields predominantly the corresponding 6, 7, 8-trihydroxy derivative II. The analogously substituted 3, 4-dihydroisoquinoline IV and isoquinoline XXI are converted into their 6, 8-dimethoxy-7-hydroxy derivatives V and XXII under these conditions. The constitution of these phenols was established by synthesis and degradation.

Related Articles:

Syntheses of Two Cytotoxic Sinapyl Alcohol Derivatives and Isolation of Four New Related Compounds from Ligularia n elumbifolia

[Battersby, Alan R.; Jones, Raymond C. F.; Kazlauskas, Rymantas; Thornber, Craig W.; Ruchirawat, Somsak; Staunton, James Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2016 - 2029]

Syntheses of Two Cytotoxic Sinapyl Alcohol Derivatives and Isolation of Four New Related Compounds from Ligularia n elumbifolia

[Battersby, Alan R.; Jones, Raymond C. F.; Kazlauskas, Rymantas; Thornber, Craig W.; Ruchirawat, Somsak; Staunton, James Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2016 - 2029]

Syntheses of Two Cytotoxic Sinapyl Alcohol Derivatives and Isolation of Four New Related Compounds from Ligularia n elumbifolia

[Battersby, Alan R.; Jones, Raymond C. F.; Kazlauskas, Rymantas; Thornber, Craig W.; Ruchirawat, Somsak; Staunton, James Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2016 - 2029]

Syntheses of Two Cytotoxic Sinapyl Alcohol Derivatives and Isolation of Four New Related Compounds from Ligularia n elumbifolia

[Battersby, Alan R.; Jones, Raymond C. F.; Kazlauskas, Rymantas; Thornber, Craig W.; Ruchirawat, Somsak; Staunton, James Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2016 - 2029]

More Articles...