Tetrahedron letters

Synthesis of γ-hydroxy ketones by LiClO 4-catalyzed addition of lithium enolates to 1, 2-Epoxides

M Chini, P Crotti, L Favero, M Pineschi

Index: Chini, Marco; Crotti, Paolo; Favero, Lucilla; Pineschi, Mauro Tetrahedron Letters, 1991 , vol. 32, # 51 p. 7583 - 7586

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Citation Number: 34

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A simple, efficient, anti-stereoselective, highly regioselective method is described for the synthesis of γ-hydroxy ketones by the direct opening of 1,2-epoxides with lithium enolates derived from simple ketones in anhydrous THF, in the presence of LiClO 4 . ... A simple, efficient, anti- ...