A Kinetic and Structural Investigation of DNA??Based Asymmetric Catalysis Using First??Generation Ligands

…, A Meetsma, BL Feringa, G Roelfes

Index: Rosati, Fiora; Boersma, Arnold J.; Klijn, Jaap E.; Meetsma, Auke; Feringa, Ben L.; Roelfes, Gerard Chemistry - A European Journal, 2009 , vol. 15, # 37 p. 9596 - 9605

Full Text: HTML

Citation Number: 48

Abstract

Abstract The recently developed concept of DNA-based asymmetric catalysis involves the transfer of chirality from the DNA double helix in reactions using a noncovalently bound catalyst. To date, two generations of DNA-based catalysts have been reported that differ in the design of the ligand for the metal. Herein we present a study of the first generation of DNA-based catalysts, which contain ligands comprising a metal-binding domain linked ...