Modulators of the human CCR5 receptor. Part 2: SAR of substituted 1-(3, 3-diphenylpropyl)-piperidinyl phenylacetamides
…, S McLaughlin, J Oldfield, JS Shaw, H Tucker…
Index: Cumming, John G.; Cooper, Anne E.; Grime, Ken; Logan, Chris J.; McLaughlin, Sharon; Oldfield, John; Shaw, John S.; Tucker, Howard; Winter, Jon; Whittaker, David Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 22 p. 5012 - 5015
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Citation Number: 29
Abstract
Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... SAR and DMPK studies led to the identification of substituted N-alkyl-N-[1-(3,3-diphenylpropyl)piperidin -4-yl]-2-phenylacetamides as potent and orally bioavailable ligands for the human CCR5 chemokine receptor. ... SAR and DMPK studies led to the identification of substituted N-alkyl-N-[1-(3, ...
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