(1??PYRENYL) METHYL CARBAMATES FOR FLUORESCENT “CAGED” AMINO ACIDS AND PEPTIDES

…, S Yamashita, T Furuta, M Iwamura

Index: Okada, Shigeto; Yamashita, Senichi; Furuta, Toshiaki; Iwamura, Michiko Photochemistry and Photobiology, 1995 , vol. 61, # 5 p. 431 - 434

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Citation Number: 16

Abstract

Abstract A highly fluorescent 1-pyrenylmethyloxycarbonyl amino acid (Pmoc-amino acid) is obtained in moderate yield by the reaction of (1-pyrenylmethyl)-4-nitrophenylcarbonate with an amino acid in the presence of sodium carbonate. The condensation of Pmoc-amino acid with an amino acid gives Pmoc-peptide in the presence of 1-ethyl-3-(3- dimethylaminepropyl) carbodiimide and 1-hydroxyben-zotriazole. The amino acid is ...