C-Glucosylflavonoid biosynthesis from 2-hydroxynaringenin by Desmodium uncinatum (Jacq.)(Fabaceae)

ML Hamilton, JC Caulfield, JA Pickett, AM Hooper

Index: Hamilton, Mary L.; Caulfield, John C.; Pickett, John A.; Hooper, Antony M. Tetrahedron Letters, 2009 , vol. 50, # 40 p. 5656 - 5659

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Citation Number: 18

Abstract

[2′, 3′, 5′, 6′-2H4]-2-Hydroxynaringenin is synthesised and incubated with commercially available UDP-glucose and the crude protein extract from Desmoduim uncinatum leaves. The organic extract produces isotopically labelled [2′, 3′, 5′, 6′- 2H4]-vitexin and [2′, 3′, 5′, 6′-2H4]-isovitexin. Repeating the experiment with denatured protein or replacing the 2-hydroxynaringenin with [2′, 3′, 5′, 6′-2H4]- ...