Tetrahedron Letters

Highly efficient one-pot C-, N-and O-acylation of indolin-2-one analogs

M Jha, B Blunt

Index: Jha, Mukund; Blunt, Brian Tetrahedron Letters, 2009 , vol. 50, # 44 p. 6044 - 6047

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Citation Number: 16

Abstract

A highly efficient one-pot multiple acylation at chemically non-equivalent sites on indolin-2- one and related motifs using 4-(N, N-dimethylamino) pyridine as a catalyst is described. This procedure gives extremely facile entry to highly desired 3-acyl-2-hydroxy-indole synthons