Semipinacol rearrangements involving trifluoromethylphenyl groups
FE Blanco, FL Harris
Index: Blanco,F.E.; Harris,F.L. Journal of Organic Chemistry, 1977 , vol. 42, # 5 p. 868 - 871
Full Text: HTML
Citation Number: 3
Abstract
Discussion The migration ratios (phenyl= 1.0) observed for the trifluoromethylphenyl groups (see Table I) are less than 1. In general, for cases in which the migration terminus is primary, the relative migratory aptitudes of aryl groups during deamination of amino alcohols follow the order expected from consideration of relative rates of electrophilic aromatic sub-stitution. 4 Some representative examples4 are p-methoxyphenyl, 1.5; p-tolyl, 1.3; p-chlorophenyl, ...
Related Articles:
[May, Scott A.; Johnson, Martin D.; Braden, Timothy M.; Calvin, Joel R.; Haeberle, Brian D.; Jines, Amy R.; Miller, Richard D.; Plocharczyk, Edward F.; Rener, Gregory A.; Richey, Rachel N.; Schmid, Christopher R.; Vaid, Radhe K.; Yu, Hannah Organic Process Research and Development, 2012 , vol. 16, # 5 p. 982 - 1002]