Synthesis, antitumor activity, and nephrotoxicity of the optical isomers of 2??aminomethylpyrrolidine (1, 1??cyclobutane??dicarboxylato) platinum (II)

K Morikawa, M Honda, KI Endoh…

Index: Journal of Pharmaceutical Sciences, , vol. 80, # 9 p. 837 - 842

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Citation Number: 19

Abstract

... Journal of Pharmaceutical Sciences / 839 Vol. ... 6.2 g, 88.4%) as a colorless crystal in the same manner as described for 4a: mp 97-98 "C (lit.'' mp, 97 "0; 'H NMR (60 MHz, CDC1,): 6 1.42-2.35(m, 4H), 2.58 (s, lH, NH), 2.95 (t, J = 6 Hz ... 840 I Joumal of Pharmaceutical Sciences Vol. ...