Organic letters

Toward the development of a general chiral auxiliary. 9. Highly diastereoselective alkylations and acylations to form tertiary and quaternary centers

RK Boeckman, DJ Boehmler, RA Musselman

Index: Schoellkopf, Ulrich; Lonsky, Ralph Synthesis, 1983 , # 8 p. 675 - 676

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Citation Number: 38

Abstract

... 4 Recent advances have also been made in catalytic asymmetric alkylation, particularly as applied to α-amino acid synthesis. ... 4 R 1, R 2 X, dr a, yield (%), product. a CH 3, CH 2 CHCH 2 Br, 49:1, 90, 7. a CH 3, PhCH 2 Br, 99:1, 89 b, 8. a CH 3, PMBOCH 2 CH CHCH 2 I, 99:1, 70, ...