2-Alkylidene-benzo [1, 3] dioxin-4-ones: a new class of compounds
P Babin, B Bennetau
Index: Babin, Pierre; Bennetau, Bernard Tetrahedron Letters, 2001 , vol. 42, # 31 p. 5231 - 5233
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Citation Number: 3
Abstract
A new class of compounds, 2-alkylidene-benzo [1, 3] dioxin-4-ones, have been synthesised by cyclisation of the corresponding o-acyloxy benzoyl chlorides with triethylamine. The 2- methylene-benzo [1, 3] dioxin-4-one acts as a prodrug for aspirin and is a useful intermediate in the synthesis of new aspirin prodrugs.
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