Tetrahedron letters

Synthesis of N-heterocyclic diols by diastereoselective pinacol coupling reactions

S Handa, MS Kachala, SR Lowe

Index: Handa, Sandeep; Kachala, Manpreet S.; Lowe, Sarah R. Tetrahedron Letters, 2004 , vol. 45, # 2 p. 253 - 256

Full Text: HTML

Citation Number: 15

Abstract

The pinacol coupling reaction has enjoyed a recent resurgence as a synthetic method due to the advent of a variety of low-valent metal reagents capable of affecting this transformation under mild reaction conditions and with excellent yields and stereoselectivities. 1 However, whilst the use of intramolecular pinacol couplings for the generation of carbocycles is well documented, 2 there are relatively few examples of the same reaction being applied to ...