Phenyliodine Diacetate??Mediated para??Functionalizations of Amido??and Amino??Substituted [2.2] Paracyclophanes

H Baars, G Raabe, I Atodiresei…

Index: Schaal, Petra; Baars, Hannah; Raabe, Gerhard; Atodiresei, Iuliana; Bolm, Carsten Advanced Synthesis and Catalysis, 2013 , vol. 355, # 13 p. 2506 - 2512

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Abstract

Abstract: The reaction of N-[2.2] paracyclophanylsubstituted amides or amines with phenyliodine diacetate (PIDA) and protic nucleophiles affords mixed para-substituted [2.2] paracyclophane derivatives in moderate to good yields. As protic nucleophiles carboxylic acids and alcohols as well as pyridine hydrobromide can be used. 4-Hydroxy- ACHTUNGTRENNUNG [2.2] paracyclophane reacts in an analogous manner. Keywords: ...