A 5C+ 5C bicycloaromatization reaction via an aldol condensation cascade. A regioselective synthesis of functionalized naphthalenes from acyclic precursors
D Stossel, TH Chan
Index: Stossel, D.; Chan, T. H. Journal of Organic Chemistry, 1988 , vol. 53, # 21 p. 4901 - 4908
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Citation Number: 15
Abstract
It is recognized that one of the important pathways in nature to assemble polycyclic compounds is the aldol-type reaction of 8-polyketide In the laboratory, the controlled aldol condensation of these precursors inspired by biogenetic considerations has been extensively studied by Harris. This has been applied in an elegant fashion to a biomimetic synthesis of 6-methylpretetramide. 6 However, the success of this approach is still ...
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