Préparation stéréosélective de méthyle cétones α-bromées: stéréochimie de l'addition d'anions en α d'un groupe sulfone sur des cyclohexanones …

…, M Charpentier-Morize, J Sansoulet

Index: Begue, Jean-Pierre; Bonnet-Delpon, Daniele; Charpentier-Morize, Micheline; Sansoulet, Jean Canadian Journal of Chemistry, 1982 , vol. 60, p. 2087 - 2092

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Citation Number: 4

Abstract

This work describes stereochemical results obtained for the preparation of α-bromomethyl ketones or α-bromoaldehydes starting from monocyclic and steroid cyclohexanones, using the Durst method. In all the cases studied here, the bromine is introduced selectively in the equatorial position. However, for monocyclic compounds, the yields of α-bromocarbonyl compounds are limited by the competitive formation of α-ethylenic carbonyl compounds.