Tetrahedron letters

Synthesis of N-phosphoryl amino acids using bis (9-fluorenylmethyl) phosphite

LY Wu, CE Berkman

Index: Wu, Lisa Y.; Berkman, Clifford E. Tetrahedron Letters, 2005 , vol. 46, # 32 p. 5301 - 5303

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Citation Number: 6

Abstract

Bis (9-fluorenylmethyl) phosphite (BFMP) was found to be an effective reagent for the N- phosphorylation of various amino acid methyl esters. BFMP was prepared from N, N- diisopropyl phosphoramidous dichloride in a one-pot two-step reaction and was obtained as