Chemistry Letters

Intramolecular oxidative coupling of brominated 2, 4'-dihydroxydiarylmethanes. A biogenetic synthesis of thelepin and its analogs.

O Tsuge, H Watanabe, S Kanemasa

Index: Tsuge, Otohiko; Watanabe, Haruyuki; Kanemasa, Shuji Chemistry Letters, 1984 , p. 1415 - 1418

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Citation Number: 7

Abstract

Oxidation of brominated 2, 4'-dihydroxydiarylmethanes with aqueous NaOCl under phase- transfer catalysis or NaOCl on Celite afforded new spiro-p-quinol ethers. Thelepin, which was isolated from the marine annelid Thelepus setosus, was first synthesized from thelephenol by these methods.