Tetrahedron

Unexpected route for the synthesis of N, N-dialkyl formamidines using phenyl chloroformate and N, N-dialkyl formamides

SH Kwak, YD Gong

Index: Kwak, Se Hun; Gong, Young-Dae Tetrahedron, 2013 , vol. 69, # 34 p. 7107 - 7111

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Abstract

Formamidines are the key intermediates for the construction of heterocycles 1, 1a, 1b, 1c, 1d, 1e, 1f, 1g and 1h and functional group transformations. 2 They have also been employed as pharmacological agents, 3, 3a and 3b protecting groups for primary amines, 4, 4a and 4b