Synlett

Synthesis of Diphenyl (nitroaryl) phosphine Oxides via Oxidative Nucleophilic Substitution of Hydrogen in Nitroarenes with Diphenylphosphine Anion

M Mąkosza, M Paszewski, D Sulikowski

Index: Makosza, Mieczyslaw; Paszewski, Maciej; Sulikowski, Daniel Synlett, 2008 , # 19 p. 2938 - 2940

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Citation Number: 13

Abstract

Potassium and sodium salts of diphenylphosphine add to nitroarenes in the position ortho and para to the nitro group. Subsequent oxidation of σ H -adducts with potassium permanganate gave diphenyl(nitroaryl)phosphine oxides. ... In this letter we report that diphenyl-[o(p)-nitroaryl ]phosphinoxides can be synthesized via oxidative nucleophilic substitution of hydrogen (ONSH) in nitroarenes with anion of diphenylphosphine. ... Oxidative nucleophilic ...

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