Iron (III)??Catalyzed Denitration Reaction: One??Pot Three??Component Synthesis of Imidazo [1, 2??a] pyridine Derivatives

…, H Zhang, S Yang, X Ren, J Li, G Huang

Index: Yan, Hao; Wang, Yuling; Pan, Congming; Zhang, Hao; Yang, Sizhuo; Ren, Xiaoyu; Li, Jian; Huang, Guosheng European Journal of Organic Chemistry, 2014 , vol. 2014, # 13 p. 2754 - 2763

Full Text: HTML

Citation Number: 18

Abstract

Abstract An iron (III)-catalyzed one-pot three-component cross-coupling nitration reaction of 2-aminopyridines, aldehydes and nitroalkanes, straightforwardly forms imidazo [1, 2-a] pyridine derivatives and is described in this report. The system shows good functional-group tolerance and proceeds smoothly in moderate to good yields.

Related Articles:

Copper??Catalyzed Aerobic Oxidative C H Functionalization of Substituted Pyridines: Synthesis of Imidazopyridine Derivatives

[Yu, Jipan; Jin, Yunhe; Zhang, Hao; Yang, Xiaobo; Fu, Hua Chemistry - A European Journal, 2013 , vol. 19, # 49 p. 16804 - 16808]

CuI-Catalyzed Aerobic Oxidative α-Aminaton Cyclization of Ketones to Access Aryl or Alkenyl-Substituted Imidazoheterocycles

[Zhang, Yuhong; Zhang, Yuanfei; Chen, Zhengkai; Wu, Wenliang; Su, Weiping Journal of Organic Chemistry, 2013 , vol. 78, # 24 p. 12494 - 12504]

Regioselective synthesis of 2-and 3-substituted imidazo [1, 2-a] pyridines

[Liu, Guoping; Cong, Xuefeng; He, Jiaheng; Luo, Shunzhong; Wu, Di; Lan, Jingbo Journal of Chemical Research, 2012 , vol. 36, # 12 p. 687 - 690]

Bis-cationic heteroaromatics as macrofilaricides: synthesis of bis-amidine and bis-guanylhydrazone derivatives of substituted imidazo [1, 2-a] pyridines

[Sundberg, Richard J.; Biswas, Sujay; Murthi, Krishna Kumar; Rowe, Donna; McCall, John W.; Dzimianski, Michael T. Journal of Medicinal Chemistry, 1998 , vol. 41, # 22 p. 4317 - 4328]

Bis-cationic heteroaromatics as macrofilaricides: synthesis of bis-amidine and bis-guanylhydrazone derivatives of substituted imidazo [1, 2-a] pyridines

[Sundberg, Richard J.; Biswas, Sujay; Murthi, Krishna Kumar; Rowe, Donna; McCall, John W.; Dzimianski, Michael T. Journal of Medicinal Chemistry, 1998 , vol. 41, # 22 p. 4317 - 4328]

More Articles...