The Reaction of Diphenyl (trimethylsilylmethyl) phosphine with Carbonyl Compounds in the Presence of Fluorides

T Kawashima, N Mitsuda, N Inamoto

Index: Kawashima, Takayuki; Mitsuda, Noriaki; Inamoto, Naoki Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 2 p. 708 - 710

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Citation Number: 4

Abstract

Diphenyl (trimethylsilylmethyl) phosphine (1) was allowed to react with benzophenone in the presence of CsF in N, N-dimethylformamide to give a mixture of methyldiphenylphosphine (2),(2, 2-diphenyl-2-trimethylsiloxyethyl) diphenylphosphine (3) and (2-hydroxy-2, 2- diphenylethyl) diphenylphosphine (4) in good yield. The use of about 10 mol% of CsF gave 3 with fairly good selectivity. The reaction with benzaldehyde gave a similar result, but ...